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Hojin Choi Selected Research

methyl- 4- (3- chloro- 4- methoxybenzylamino)- 8- (2- hydroxyethyl)- 7- methoxyquinazolin- 6- ylmethylcarbamate

1/2010Discovery of potent, selective, and orally bioavailable PDE5 inhibitor: Methyl-4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-ylmethylcarbamate (CKD 533).

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Hojin Choi Research Topics

Disease

6Dementia (Dementias)
01/2022 - 01/2018
6Ischemic Stroke
04/2019 - 10/2012
5Alzheimer Disease (Alzheimer's Disease)
01/2022 - 01/2012
4Neoplasms (Cancer)
10/2019 - 09/2010
4Cerebral Infarction
04/2019 - 10/2015
3Cognitive Dysfunction
09/2021 - 01/2017
2Brain Ischemia (Cerebral Ischemia)
09/2021 - 10/2019
2Hypoxia (Hypoxemia)
01/2019 - 10/2012
2Neurodegenerative Diseases (Neurodegenerative Disease)
03/2018 - 01/2012
2Hypertension (High Blood Pressure)
09/2017 - 10/2015
2B-Cell Lymphoma (Lymphoma, B Cell)
12/2016 - 10/2012
2Inflammation (Inflammations)
06/2012 - 05/2012
2Erectile Dysfunction
01/2010 - 12/2008
1Reperfusion Injury
09/2021
1Stroke (Strokes)
09/2021
1Glioblastoma (Glioblastoma Multiforme)
10/2020
1Tolosa-Hunt Syndrome
04/2020
1painful Ophthalmoplegia
04/2020
1Meningioma (Meningiomas)
10/2019
1Brain Neoplasms (Brain Tumor)
10/2019
1Pituitary Neoplasms (Pituitary Adenoma)
10/2019
1Neuroblastoma
10/2019
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
03/2018
1Parkinson Disease (Parkinson's Disease)
01/2018
1Dyskinesias (Dyskinesia)
01/2018
1Mitochondrial Diseases (Mitochondrial Disease)
01/2018
1Amyloid Plaque
12/2017
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
10/2015
1Infarction (Infarctions)
10/2015
1Lacunar Stroke
03/2015
1Brain Infarction
03/2015
1Nervous System Diseases (Neurological Disorders)
01/2013
1Pain (Aches)
06/2012
1Atopic Dermatitis (Atopic Eczema)
06/2012
1Body Weight (Weight, Body)
06/2012

Drug/Important Bio-Agent (IBA)

5Neuroprotective AgentsIBA
09/2021 - 10/2015
5Proteins (Proteins, Gene)FDA Link
10/2020 - 10/2012
3Glucose (Dextrose)FDA LinkGeneric
09/2021 - 12/2016
3Oxygen (Dioxygen)IBA
09/2021 - 12/2016
3Pharmaceutical PreparationsIBA
12/2020 - 01/2018
2Intracellular Signaling Peptides and ProteinsIBA
10/2019 - 10/2012
2Glycogen Synthase Kinase 3IBA
01/2018 - 10/2012
2Acetic Acid (Vinegar)FDA LinkGeneric
06/2012 - 05/2012
2NitritesIBA
06/2012 - 05/2012
2CarrageenanIBA
06/2012 - 05/2012
2Valine (L-Valine)FDA Link
11/2010 - 09/2010
2ProdrugsIBA
11/2010 - 09/2010
2Tubulin ModulatorsIBA
11/2010 - 09/2010
1Donepezil (Aricept)FDA LinkGeneric
01/2022
1Indicators and Reagents (Reagents)IBA
01/2022
1Amyloid (Amyloid Fibrils)IBA
09/2021
1Adrenal Cortex Hormones (Corticosteroids)IBA
04/2020
1Methotrexate (Mexate)FDA LinkGeneric
04/2020
1Small Interfering RNA (siRNA)IBA
10/2019
1Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA
10/2019
1L-Type Calcium Channels (Dihydropyridine Receptor)IBA
10/2019
1Amlodipine (Norvasc)FDA LinkGeneric
10/2019
1polyacrylamideIBA
10/2019
1Leucine (L-Leucine)FDA Link
10/2019
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
10/2019
1Atorvastatin (Lipitor)FDA Link
04/2019
1Phosphotransferases (Kinase)IBA
01/2019
1ZincIBA
01/2019
1Acetylcarnitine (Alcar)IBA
03/2018
1quinone (benzoquinone)IBA
01/2018
1Clopidogrel (Plavix)FDA Link
01/2018
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2018
1Cholinesterase Inhibitors (Anticholinesterases)IBA
01/2018
1Glycogen Synthase (Synthase I)IBA
01/2018
1Levodopa (L Dopa)FDA LinkGeneric
01/2018
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
01/2018
1CateninsIBA
01/2018
1SynucleinsIBA
01/2018
1Amyloid beta-PeptidesIBA
12/2017
1candesartanIBA
09/2017
1Angiotensin Receptor AntagonistsIBA
09/2017
1Glycogen Synthase KinasesIBA
12/2016
1Therapeutic UsesIBA
10/2015
1Antihypertensive Agents (Antihypertensives)IBA
10/2015
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
10/2015
1cilnidipineIBA
10/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2015
1Biomarkers (Surrogate Marker)IBA
03/2015
1HMGB1 Protein (HMG1)IBA
03/2015
1Macrophage Migration-Inhibitory FactorsIBA
03/2015
1coenzyme Q10 (CoQ10)IBA
10/2012
1Free RadicalsIBA
10/2012
1Caspase 3 (Caspase-3)IBA
10/2012
1Phospholipids (Phosphatides)FDA LinkGeneric
06/2012
1LipopolysaccharidesIBA
05/2012
1Radioisotopes (Radionuclides)IBA
05/2012

Therapy/Procedure

4Activities of Daily Living (ADL)
01/2021 - 01/2017
4Therapeutics
12/2016 - 12/2008
1Patient Care
01/2022
1Chemoradiotherapy
10/2020
1Medical Day Care (Partial Hospitalization)
08/2020
1Cognitive Training
08/2020
1Aftercare (After-Treatment)
10/2012
1Secondary Prevention
10/2012
1Oral Administration
06/2012